I was debating on whether to switch my line but decided to stay with Advanced Nutrients sensi because I am familiar with it and can look at a plant and know what strength dose to give it. I figured changing medium and nutrient lines would be to much room for error even following their chart I grow alot of diffrent strains and some very nute sensitive. And I start at 1/3 rec strength and do the same by waiting to I see a little burn then back her off and keep her on the edge. My tap waters to high in iron and really messes with the medium so I had to get a RO system. But I have to watch for micro deficiencies bc of the water being so low in minerals. My Ppm is 3.lolNo, I use tap water. My tap water is good with a starting PPM 100. You will not have any deficiencies if you use a nutrient line designed for what we are doing. Use only one line, use the entire line and follow their chart. When new to a nutrient line I always start at 50% strength and work up until slight tip burn then back off 10%. Once you are familiar with a line you can go with what you know works.