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Discussion in 'Medical Cannabis Discussion' started by Eyes on Fire, Mar 10, 2014.

  1. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    yeah man,I bet that works really sweet for ya dude.NO problem man.I do this for myself too.ya know to just understand why I hurt the way i do and not go frigin crazy cuz of ringing in my ears,eye issues n the nerve stuff is awesome too.LOL!Im really glad it helps you too brother.pain is pain but thats what makes MS a lil bit apart from other heavy diseases,is the nerve issues and they love to change up on ya.thats what I hate.if it was to stay in one area or two,nooo worries,but nooooo,couldnt have that LMFAO!!!"AFN smoke out""AFN smoke out"
  2. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    The Healing Properties of Cannabis.

    Goober Evening everyone, :smoke:

    I was bouncing about as per usual n saw this cool thing done by 420 magazine n thought some could use the reference and the links if they good everyone.

    in case anyone likes that sorta thing,I was watching Through The Wormhole with Morgan Freeman.its this Theoretical Physics TV Show thats pretty decent.Check it out.L8r everyone.
    "AFN smoke out""AFN smoke out""AFN smoke out""AFN smoke out"

    [h=1]The Healing Properties Of Cannabis[/h]March 31, 2010 By 420 8 comments
    We have compiled the following list as a reference point for those seeking research and information on the numerous healing properties of Cannabis. This miraculous herb alleviates the symptoms of everything from hiccups to Multiple Sclerosis. When making personal decisions about your health, information is golden. It’s your body and we think it is important for you to be knowledgable about the scientific studies and anectodal evidence that supports Cannabis as a viable treatment for your ailments.
    Marijuana-like Compounds May Aid Array Of Debilitating Conditions
    The Forgotten Medicine – A Look At The Medical Uses Of Cannabis
    The Endo-Cannabinoid System
    Human Studies on Medical Uses of Marijuana

    Cannabis Myths
    Safe to Smoke – Vaporizing Cannabinoids
    The Myth of Marijuana’s Gateway Effect
    Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways
    Amotivational Syndrome
    Documented Safety of Long Term Cannabis Use
    Side Effects of Cannabis Use

    Accepted Medical Uses
    Accepted Medical Use: Clinical Research
    Accepted Medical Use of Cannabis: Basic Research
    Accepted Medical Use of Cannabis: Reviews of Earlier Clinical Studies
    Accepted Medical Use: Patient Experiences
    Accepted Medical Use of Cannabis: Reviews of Earlier Clinical Studies
    Accepted Medical Use: Pharmaceutical Industry

    Cannabis as a Substitute for Alcohol

    ALS – Amyotrophic Lateral Sclerosis – Lou Gehrigs Disease
    Marijuana In The Management Of Amyotrophic Lateral Sclerosis (ALS)

    Alzheimers Disease
    Marijuana’s Active Ingredient Shown to Inhibit Primary Marker of Alzheimer’s
    Study: Marijuana Slows Alzheimer’s Decline
    Marijuana And Alzheimer’s Disease

    Anti-Bacterial Qualities
    Antibacterial Cannabinoids from Cannabis Sativa

    Rheumatoid Arthritis – Cannabis Eases Pain And Suppresses Disease
    Anti-inflammatory Compound From Cannabis Found In Herbs
    Marijuana And Arthritis

    Smoked Cannabis And Asthmatics
    Acute Effects Of Smoked Marijuana And Oral Delta-9-Tetrahydrocannabinol In Asthmatics
    Marijuana And Asthma

    Attention Deficit Disorder And ADHD
    Cannabis As A Medical Treatment For Attention Deficit Disorder
    Marijuana and ADD Therapeutic Uses
    Autism, ADD, ADHD and Marijuana Therapy
    Smoked Marijuana Improved ADHD Driver’s Performance

    Sam’s Story – Using Medical Cannabis to Treat Autism Spectrum Disorder
    Autism, ADD, ADHD and Marijuana Therapy
    Autism Ritalin and Cannabis

    Body Temperature
    A Cooling Effect From Cannabis?

    The Brain
    Marijuana May Spur New Brain Cells
    Marijuana-Like Chemicals in the Brain Calm Neurons
    Marijuana And The IQ
    New Brain Cells Implicated In Machinery Of Cannabinoid Signaling
    Endocannabinoids The Brain Demonstrate Novel Modes Of Action When Stressed

    Pot’s Cancer-Healing Properties
    Lung Cancer: Antineoplastic Activity Of Cannabinoids
    Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth
    Pot Compound Enhances Efficacy Of Anti-Cancer Agents, Study Says
    Marijuana & Skin Cancer
    Marijuana’s Active Ingredient Kills Leukemia Cells
    Cannabis Extract Makes Brain Tumors Shrink, Halts Growth Of Blood Vessels
    Marijuana Compound Inhibits Breast Cancer Growth
    Marijuana And Chemotherapy

    Crohn’s Disease
    Marijuana And Crohn’s Disease/Gastrointestinal Disorders

    Depression – Bi-polar
    Cannabis and Depression
    Synthetic THC Is Anti-Depressant In Small Dose, Makes Depression Worse At Higher Dose
    Cannabinoids Elicit Antidepressant-Like Behavior and Activate Serotonergic Neurons
    Marijuana and Bipolar Disorder
    Cannabinoids in Bipolar Disorder
    The Use of Cannabis as a Mood Stabilizer

    Cannabis And Diabetic Retinopathy
    Medical Breakthrough! Medicinal Marijuana for Diabetics!
    Marijuana Controls Diabetes – Marijuana Compound May Help Stop Diabetic Retinopathy
    Diabetes & Marijuana

    Hypnotic and Antiepileptic Effects of Cannabidiol
    Cannabis May Help Epileptics
    Cannabidiol And Epileptic Patients

    Synthetic Cannabinoid May Aid Fertility In Smokers

    THC Reduces Pain in Fibromyalgia Patients
    Cannabis And Fibromyalgia
    Fibromyalgia: Effective Treatment with Medical Marijuana
    Marijuana-Based Drug May Ease Fibromyalgia Pain

    National Eye Institute Policy on Marijuana
    Cannabis and Neuroprotection
    Marijuana And Glaucoma

    Cannabis As A Treatment For PMS And Other Female Ailments

    Heart Disease And Cardiovascular Disorders
    Cannabis Use Not Associated With Risk Factors For Diseases Of Heart And Circulation
    Cannabinoids Prevented The Development Of Heart Failure In Animal Study
    Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks
    Cannabinoid Offers Cardioprotection, Study Says
    Does Cannabis Hold the Key to Treating Cardiometabolic Disease?
    Marijuana Chemical Fights Hardened Arteries

    Hepatitis C
    Cannabis Improves Outcomes For Hepatitis C Patients
    Cannabis – Improved Treatment Response in Hepatitis C Patients
    Hepatitis C positive people – Use and self-medication with Cannabis
    Cannabis Use Can Improve Effectiveness of Hepatitis C Therapy
    Marijuana And Hepatitis C

    Herpes Viruses
    Cannabis May Help Combat Cancer-causing Herpes Viruses

    Marijuana Cures Hiccups

    HIV – AIDS
    Medicinal Marijuana Eases Neuropathic Pain in HIV
    Marijuana And AIDS (HIV) & AIDS Wasting
    Marijuana And The Immune System

    Huntingtons Disease
    Cannabinoids And Huntingtons Disease

    Study Shows Long Term Marijuana Users Healthy
    Marijuana Smoking Doesn’t Lead to Higher Death Rate

    Lower GI Conditions (Stomach Problems)
    Cannabinoid Activator Mellows Out Colon
    Anti-inflammatory Compound From Cannabis Found In Herbs
    Cannabis May Soothe Inflamed Bowels
    Medical Marijuana In The Treatment Of Digestive Disorders
    Marijuana And Crohn’s Disease/Gastrointestinal Disorders

    Cannabis and Systemic Lupus Erythematosus

    Mad Cow Disease
    Cannabidiol May Be Effective In Preventing Mad Cow Disease

    Mental Health
    American Psychiatric Association Assembly Unanimously Backs Medical Marijuana
    Cannabis As A Psychotropic Medication
    Cannabis Does Not Induce Schizophrenia, Dutch Scientists Say
    Study: Marijuana Eases Traumatic Memories
    Marijuana, Genes, Medicines And Brain Scans Help Scientists Find Anxiety Treatment
    Cannabis and Aggression
    Cannabis as a First-line Treatment for Childhood Mental Disorders
    Marijuana And Psychological Conditions
    Cannabidiol, A Cannabis Sativa Constituent, As An Antipsychotic Drug

    Migraine Headache – Headaches
    Cannabis And Marinol In The Treatment Of Migraine Headache
    Medical Marijuana: Headaches/Migraines

    Multiple Sclerosis
    MMJ: National MS Society Takes Half-Step Toward Recognizing Therapeutic Uses
    Cannabinoids And Multiple Sclerosis
    Marijuana Helps MS Patients Alleviate Pain, Spasms
    Marijuana And Multiple Sclerosis / Muscle Spasms

    Neuropathic Pain
    Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain
    Medicinal Marijuana Eases Neuropathic Pain in HIV
    Marijuana May Be Effective for Neuropathic Pain

    The Science of Why Pot Makes You Hungry

    Hebrew U. Researchers Find Cannabis Can Strengthen Bones
    New Weapon In Battle Against Osteoporosis

    Pain Management
    Cannabis Effective At Relieving Pain After Major Surgery
    An Ancient Look at a New Medical Approach for Pain
    Pharmacokinetics And Cannabinoid Action Using Oral Cannabis Extract
    Dr. Robert V. Brody: Declaration. Cannabis and Hospice Ethics – pain management
    Pain Management With Cannabis
    Finding the Dose Window For Optimal Pain Relief from Cannabis
    Marijuana And Pain / Analgesia
    Morphine-Cannabis Super-Painkiller

    Parkinson’s Disease
    Neuroprotection in Parkinson’s Disease: Modafinil and ?9-tetrahydrocannabinol
    Marijuana-like Substance in Brain Could Help Treat Parkinson’s

    Post-traumatic Stress Disorder (PTSD)
    Medical Marijuana – PTSD and the Iraq Veteran
    For Veterans with PTSD, Marijuana Can Mean Life
    PTSD and Cannabis: A Clinician Ponders Mechanism of Action
    Cannabis Eases Post Traumatic Stress Disorder
    Pot-Like Chemical Helps Beat Fear
    Treatment for PTSD Should Include Cannabis
    Essay: Medical Marijuana And The Iraq Veteran

    Potential for Abuse
    Potential for Abuse: Abuse of Cannabis
    Potential for Abuse: Use and Abuse
    Potential for Abuse: Cannabis and Dronabinol
    Dependence Liability: Basic Research on Rewarding Tolerance and Withdrawl

    Prenatal Marijuana Use And Neonatal Outcome
    Cannabis Relieves Morning Sickness
    Dreher’s Jamaican Pregnancy Study
    Use of Marijuana During Pregnancy
    Medical Marijuana: A Surprising Solution to Severe Morning Sickness
    Scientists Measuring Natural ‘Cannabis’ In Pregnant Women

    Pulmonary Disease
    New Cannabinoid Receptor in Pulmonary Arteries

    Sickle Cell Disease
    Sickle Cell Disease and Cannabis

    Skin Disease
    Israeli Research Finds That THC Could Alleviate Allergic Skin Disease

    THC Effective In Tourette-Syndrome
    Marijuana And Tourette’s Syndrome

    I hope some of ya found it useful. :smoke:
  3. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    MSAA Amazon Donation

    Hi guys I wasnt sure if It ok to stick this in here.but if not no worries.just say something n ill get rid of it.But its prett good imo.I have another link but thats something different.But this is interesting.Thought some may use me.Be well everyone and I hope everyone is well today.
  4. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    The Sleepy Cannabinoid

    "AFN smoke out""AFN smoke out""AFN smoke out""AFN smoke out""AFN smoke out"

    Thought some of you might enjoy a wee touch of info today..Be good everyone.

    CBN: The Sleepy Cannabinoid

    What Is Cannabinol (CBN)?

    When we look at the construction of cannabis, we find that it has over 80 cannabinoids. Until recently, tetrahydrocannbinol (THC) was the only cannabinoid anyone seemed to care about. Thankfully recent research, particularly about cannabidiol (CBD), has brought about an intense interest in all the cannabinoids.
    As is the case in many of the known cannabinoids, cannabinol (CBN) stems from cannabigerolic acid (CBGA) in cannabis. The plant naturally produces enzymes (aka synthases) that convert the CBGA to one of 3 major cannabinoids:cannabichromene carboxylic acid (CBCA), cannabidiol carboxylic acid (CBDA), and tetrahydrocannabinol carboxylic acid (THCA).
    When the plant develops THCA, it usually will be converted to THC as a result of heat or UV light. That being said, THCA can be converted to CBNA over time as well. Prolonged exposure to air causes the THCA to lose hydrogen molecules and oxidize; now we have CBNA. Just like the rest of the acidic cannabinoids, CBNA will convert to cannabinol (CBN) when exposed to heat or UV light.
    What Are The Benefits Of Cannabinol (CBN)?

    Cannabis is widely used as a sleep-aid for those who suffer from insomnia and cannabinol is the reason why. By all accounts, CBN is the cannabinoid responsible for the sedative effects of cannabis. Because of this, I tend to reserve high-CBN strains for night use.
    Another use for cannabinol as an anti-bacterial. According to a Italian study from 2008, cannabinol “showed potent activity against MRSA” when applied as a topical. Topical uses also have shown promise in treating burns and psoriasis.
    The research on cannabinol (CBN) is still lacking, but some early studies have suggested it could stimulate bone growth. If that’s the case, it would be helpful in treating osteoporosis. It could also help those with broken bones to recover more quickly.
    Cannabinol Can Reflect The Age Of Your Cannabis

    When searching for the perfect strain, it’s important to know what you’re getting. This is why lab-testing should never be overlooked. Testing facilities like Steep Hill Lab in California give patients a complete cannabinoid profile of their medicine. It’s always a good idea to check a strains profile before making a decision.
    Because cannabinol is a production of degradation, it’s not usually found in high concentrations (in a collective). High levels of CBN are usually related to poor storage methods. If cannabis is stored in an airtight container of some sort, it’s unlikely that a lot of THC would convert to CBN.
    Luckily, not all is lost if you’re searching your collective for a sleep-aid. The simple solution would be to allow you’re medicine to age a bit. When exposed to the air, the THC will begin to degrade and convert to CBN, a great way to fight insomnia.
    dankstyle J likes this.
  5. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    Reversing Multiple Sclerosis

    Im not sure if ive posted this prior..I dont believe so cuz its like 20 minutes..But its an excellent source for info on MS and SEVERAL other similar diseases and how this Doctor Reversed her MS.Pretty involved but ppl get to points..n Im close if I get me some money or any other form of currency soon LOL!

    [video=youtube;KLjgBLwH3Wc] AKDX_74wn[/video]

    This video short of Pain Is pretty much how I feel as Im certain many do.Its very nice vid for others to slightly understand MS.

    This vid is an Excellent vid and excellent ppl to source n find quite good guys and very helpful too.
  6. FreeLivin

    FreeLivin The Protégé

    Dec 10, 2013
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    Hey Eyes on Fire, I wanna thank you for this, I wish information like this had been readily available in the past, ms has tormented my family for generations, all the males on my mothers side had it, grandfather, uncle, and even the females have had some mild form of it, then again all the males and females that I know of on my fathers side all died from an heart attack, grandfather at 36... nice
    Thank you again..
    Eyes on Fire likes this.
  7. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    My Pleasure sweat!! I put it here for others to comb over if they ever see MS or anything related n do a search n POP! all kinds of stuff that Ive looked at.i'll glance at some from time to time when I need to remeber a certain thing too.Glad it was useful to ya buddy!!I truly hope ya'll are havin a great times!!
    dankstyle J likes this.
  8. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    dankstyle J likes this.
  9. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    I got my New News Letter.sounds like gary gnews n the crew LOL! Kids and MS,and mistaking depression for anxiety in which is significantly much more common BTW .

    Pregnant and MS issues employment opportunities outside the home as well as from self employment n from home too. Also a great article on Microglia and Research aspects of all the current research updates.and some crackhead who has MS swimming with sharks I guess to prove he don't have a death wish !?>LMFAO I dunno:Sharing One:
    dankstyle J likes this.
  10. Eyes on Fire

    Eyes on Fire Guy Smiley

    Sep 17, 2013
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    Thought this was pretty I thought Id share it.

    [h=3]Past Evidence for Cannabinoids as Anti-Cancer Agents[/h]Prior evidence found to support the potential for cannabinoids to work as anti-cancer agents, through the prevention of cancer cell formation and division, has shown their potential influence in:

    • preventing stimulation of adenylate cyclase and protein kinase A, enzymes that lead to increased cell signaling that lead to increased growth, survival, etc.
    • stopping the process by which cells divide by preventing production of inhibiting proteins, reducing the number of receptors and molecules that lead to increased cell growth (such as the epidermal growth factor, nerve growth factor receptors, and vascular endothelial growth factor and the hormone prolactin)
    Additionally, the potential for cancer cells to invade local tissues and organs (which signifies a more aggressive cancer) is decreased by compounds that block receptors usually stimulated by endocannabinoids.
    [h=3]Results of the Study[/h]Researchers treated/examined (1) prostate cancer cells (lines PC3 and PrC) and (2) cells from patients with benign prostatic hyperplasia (BPH, a condition that results in an increased number of prostate cells that are not cancerous):

    • histologically (i.e. using a microscope): stained cells in order to visualize cannabinoid (CB1 and CB2) receptors, and
    • by treating individual cells for (1) 48 hours with 2.5, 5.0 or 10 µM of either anandamide, 2-AG, or methanandamide (endocannabinoids, i.e. cannabinoids found naturally within the body) or (2) for 30 minutes with 10 or 20 µM ofrimonabant (a CB1 receptor antagonist; an agent that prevents CB1 receptor stimulation) followed by treatment with the endocannabinoids.
    Here is what they found:

    • more CB1 and CB2 receptors found in aggressive prostate cancer cells than in less aggressive prostate cancer cells or BPH cells
    • after treatment with endocannabinoids, cell survival was decreased in a statistically significant manner (i.e. in this case, there was a less than 5% chance that these results occurred merely by chance, rather than as a direct result of treatment)
    • the higher the dose of endocannabinoid used, the greater the decrease in cell number (i.e. “dose dependence” was exhibited)- effect greatest for PC3 cells > BPH > PrC
    • although expected among PC3, PrC, or BPH cells when treated with 5 µM of endocannabinoids, the cell’s growth cycle was not inhibited in comparison to those that were untreated (dose used may not have been high enough)
    • when treated with 20 µM of the cannabinoid receptor antagonist, cell survival was not decreased- when treating the same cells with endocannabinoids, cell survival still was not decreased (likely as a result of the CB1 receptors being blocked)
    • when 10 µM of cannabinoid receptor antagonist was used followed by treatment with cannabinoids, cell survival then began to decrease in PC3 cells (i.e. not enough CB1 receptors were blocked by the antagonist in order to prevent the protective effects of the endocannabinoids)
    • between PC3 than in PrC cells, number of cells going through programmed-cell death was higher in cell lines treated with endocannabinoids than in those not being treated with endocannabinoids, with a stronger effect for PC3 cells
    • between PrC and BPH cells, after 48-treatment with 5 µM of endocannabinoids, there was an increase in caspase-3 (enzyme that helps to activate programmed cell death) and a decrease in Bcl-2 (a protein that helps to prevent programmed cell death)
    • in PrC cells, after 48-treatment with 5 µM of endocannabinoids, there weremodifications in cell signaling pathways whose over-activation is commonly associated with cancer formation and propagation- increased activity in Erk pathway, decreased activity in Akt pathway
    The authors note, “These results suggest that the effect of endocannabinoids on [prostate cancer] cells… may be caused by the activation of the apoptotic pathway… The great advantage that the use of endocannabinoids may bring to the battle against prostate cancer is that it has been demonstrated that the receptors for these molecules are substantially overexpressed in cancerous prostatic cells when compared to normal, healthy prostate tissues… Based on these results, we suggest that endocannabinoids may be a beneficial option for the treatment of prostate cancer that has become nonresponsive to common therapies.”

    [h=3]Symptom Relief[/h]Individuals with prostate cancer who are finding it difficult to control certain symptoms that may be experienced as a result of the disease or treatment with standard therapies (such as cachexia [“wasting syndrome”], anorexia [the symptom, not the disorder “anorexia nervosa”], nausea, and vomiting) may experience some relief through the use of whole-plant cannabis or the approved cannabinoid medication like dronabinol (i.e. synthetic THC; treatment with dronabinol has sometimes been associated with high levels of anxiety in patients, due to the absence of other cannabinoids to dull the impact of THC’s psychoactive effects). Whole-plant cannabis use should be carefully discussed with and monitored by a healthcare professional, and individuals using whole-plant cannabis should not expect that use will prevent or treat prostate cancer.
    [h=3]Conclusion[/h]In whole-plant or isolated forms, cannabinoid therapies have the potential to not only control symptoms caused by the disease and its treatment, but also potentially to inhibit its progression.
    Given (1) these and past results, (2) that late-stage prostate cancer patients have limited treatment options, and (3) that cannabinoid therapies have a favorable side effect profile, their use is a potential additional, experimental treatment option that is relatively safe for patients. Further research is needed in order to determine whether or not cannabinoid therapies will prove useful as a reasonable and effective option for the prevention or treatment of prostate cancer.
    Before beginning whole-plant cannabis use, individuals with prostate cancer should consult with and have any possible use monitored by a healthcare provider, so that suitable recommendations can be given, and benefits or harmful side effects can carefully monitored and addressed when necessary.

    other relative links imo. :smoke:

    [h=2]Researchers Investigate Prostate Cancer & Cannabinoid Treatments[/h][​IMG]The PC-3 cell line is often used to represent the development of human prostate cancer. According to the Spanish research team, the cell line has been found to express high levels of CB1 and CB2 receptors.
    In the past, the same research team has shown that cannabinoids can inhibit growth and even trigger apoptosis (programmed cell death) in the PC-3 cell line. This study in particular was intended to investigate the role of the CB2 receptor specifically.
    All in all, the study involved three human prostate cancer cell lines – PC-3, DU-145, and LNCaP. Researchers investigated the proliferation of prostate cancer cells in a cell culture environment while the CB2 receptors were inhibited. Prostate tumors were induced in mice as a model also.
    [h=2]Cannabinoid Treatment Inhibits Prostate Cancer Growth In Mice[/h]According to the results published in the British Journal of Cancer, the University of Alcalá research team found that a chemical similar to anandamide (the body’s natural version of THC) inhibited PC-3 cell growth. They experienced the same results with JWH-015, a synthetic CB2 receptor agonist.
    “CB[COLOR=#6350A7 !important]2 agonists have potential therapeutic interest and deserve to be explored in the management of prostate cancer.”[/COLOR] – Professor I Díaz-Laviada
    With that said, cannabinoid-induced benefits were seemingly reversed by inhibiting activation of the CB2 receptors. Cannabinoid treatments did not fight cancer cell proliferation with the same vigor once the CB2 receptors were down-regulated.
    Accordingly, the Spanish study concludes that activation of the CB2 receptors could play a major role in the inhibition of prostate cancer growth. It reads, “CB2 agonists have potential therapeutic interest and deserve to be explored in the management of prostate cancer.”

    and one more


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